| | Day | Time | | Opponent | Score | | Record | |
| February |
| % | 4 | 1:00 PM | vs. | Coastal Bend | RAIN | | |
| % | 7 | 1:15 PM | vs. | Coastal Bend | W-3-1 (8) | | |
| % | | Game 2 | vs. | Coastal Bend | L-2-3 | | |
| * | 10 | 3:00 PM | vs. | SW Assemblies of God | FORFT | | 1-0 1-0 |
| | Game postponed due to weather conditions. |
| * | 11 | 12:00 PM | vs. | SW Assemblies of God | W-8-0 (5OT) | | 2-0 2-0 |
| * | | Game 2 | vs. | SW Assemblies of God | W-9-1 (5OT) | | 3-0 3-0 |
| | 17 | 1:00 PM | @ | Texas Lutheran University | CNCL | | |
| | CANCELLED DUE TO WEATHER -- University of Houston-Victoria 2012 Softball Tournament |
| | | 3:30 PM | @ | University of Houston - Victoria | CNCL | | |
| | CANCELLED DUE TO WEATHER -- University of Houston-Victoria 2012 Softball Tournament |
| | 18 | 10:30 AM | @ | Huston-Tillotson | RAIN | | |
| | CANCELLED DUE TO WEATHER -- University of Houston-Victoria 2012 Softball Tournament |
| | | 3:30 PM | @ | Texas Lutheran University | CNCL | | |
| | CANCELLED DUE TO WEATHER -- University of Houston-Victoria 2012 Softball Tournament |
| | 19 | 1:00 PM | @ | Southwestern University | L-1-8 | | 3-1 |
| | | Game 2 | @ | Southwestern University | L-3-11 (6) | | 3-2 |
| | 21 | 3:00 PM | @ | Texas Southern University | L-8-9 | | 3-3 |
| | | Game 2 | @ | Texas Southern University | L-7-8 | | 3-4 |
| | 24 | 12:00 PM | @ | Oklahoma City University | FORFT | | 4-4 |
| | OKC 8-OLLU 0 |
| | | 1:30 PM | @ | Bellevue University | W-8-7 | | 5-4 |
| | St. Gregory's University Invitational |
| | 25 | 10:30 AM | @ | Arizona Christian | W-4-1 | | 6-4 |
| | St. Gregory's University Invitational |
| | | 4:30 PM | @ | Southern Nazarene University | W-9-7 | | 7-4 |
| | St. Gregory's University Invitational |
| | 29 | 5:00 PM | @ | Trinity University | L-3-6 | | 7-5 |
| | | Game 2 | @ | Trinity University | L-0-5 | | 7-6 |
| March |
| | 3 | 1:00 PM | vs. | Ashford University | L-5-9 (9) | | 7-7 |
| | | Game 2 | vs. | Ashford University | W-13-12 (8) | | 8-7 |
| * | 12 | 5:00 PM | @ | Langston | W-8-5 | | 9-7 4-0 |
| * | | Game 2 | @ | Langston | L-4-5 | | 9-8 4-1 |
| * | 13 | 11:00 AM | @ | Langston | L-9-10 (9) | | 9-9 4-2 |
| * | 20 | 4:00 PM | @ | Huston-Tillotson | W-8-7 | | 10-9 5-2 |
| | Make-up date will be posted as soon as it is known. |
| * | | Game 2 | @ | Huston-Tillotson | W-10-0 (5) | | 11-9 6-2 |
| * | 23 | 4:00 PM | vs. | Texas Wesleyan | W-7-1 | | 12-9 7-2 |
| * | 24 | 11:00 AM | vs. | Texas Wesleyan | W-4-3 (8) | | 13-9 8-2 |
| * | | Game 2 | vs. | Texas Wesleyan | W-5-2 | | 14-9 9-2 |
| * | 28 | 5:00 PM | @ | Huston-Tillotson | L-0-1 | | 14-10 9-3 |
| | 31 | 3:00 PM | @ | University of Houston - Victoria | L-3-7 | | 14-11 |
| | | Game 2 | @ | University of Houston - Victoria | W-7-3 (11) | | 15-11 |
| April |
| | 4 | 2:00 PM | vs. | Texas Southern University | W-5-0 | | 16-11 |
| | | Game 2 | vs. | Texas Southern University | L-3-13 (5) | | 16-12 |
| * | 6 | 1:00 PM | vs. | Southwest | L-2-3 | | 16-13 9-4 |
| * | | Game 2 | vs. | Southwest | W-5-3 | | 17-13 10-4 |
| * | 7 | 11:00 AM | vs. | Southwest | W-8-1 | | 18-13 11-4 |
| | 13 | 2:00 PM | vs. | University of Houston - Victoria | W-2-1 | | 19-13 |
| | | Game 2 | vs. | University of Houston - Victoria | L-2-10 | | 19-14 |
| * | 14 | 1:00 PM | vs. | Texas College | W-15-0 (5) | | 20-14 12-4 |
| * | | Game 2 | vs. | Texas College | W-3-0 | | 21-14 13-4 |
| * | 15 | 11:00 AM | vs. | Texas College | W-9-0 (5) | | 22-14 14-4 |
| * | 21 | 1:00 PM | vs. | Bacone | W-11-3 (5) | | 23-14 15-4 |
| * | | Game 2 | vs. | Bacone | W-6-0 | | 24-14 16-4 |
| * | 22 | 11:00 AM | vs. | Bacone | W-4-1 | | 25-14 17-4 |
| | Seniors' Day Festivities beginning at 10:45 a.m. |
| * | 27 | 4:00 PM | @ | Northwood | L-3-6 | | 25-15 17-5 |
| * | 28 | 12:00 PM | @ | Northwood | W-2-1 | | 26-15 18-5 |
| * | | Game 2 | @ | Northwood | L-4-5 | | 26-16 18-6 |
| May |
| | 3 | 3:00 PM | vs. | Northwood | W-2-1 (8) | | 27-16 |
| | RRAC Tournament in Farmers Branch, Texas |
| | 4 | 4:00 PM | vs. | Texas Wesleyan | L-1-2 (9) | | 27-17 |
| | RRAC Tournament Second Round |
| | 5 | 3:00 PM | vs. | Northwood | W-2-1 (8) | | 28-17 |
| | RRAC Tournament in Farmers Branch, Texas |
| | | 4:00 PM | vs. | Texas Wesleyan | L-2-5 | | 28-18 |
| | RRAC Tournament -- Finals |
Bacone College
Huston-Tillotson University
Jarvis Christian College
Langston University
Louisiana State University-Shreveport
Northwood University
Our Lady of the Lake
Paul Quinn College
SW Assemblies of God University
Texas College
Texas Wesleyan University
University of St. Thomas
University of Texas-Brownsville
University of the Southwest
Wiley College
